Basic, Translational, and Clinical Research

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A New Approach to an Old ProblemOne Brave Idea
James Cranley and Calum A. MacRae

Circulation Research. 2018;122:1172-1175, originally published April 26, 2018
https://doi.org/10.1161/CIRCRESAHA.118.310941

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Emerging Role of Precision Medicine in Cardiovascular Disease
Jane A. Leopold and Joseph Loscalzo

Circulation Research. 2018;122:1302-1315, originally published April 26, 2018
https://doi.org/10.1161/CIRCRESAHA.117.310782

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The Vasculature in Prediabetes
David H. Wasserman, Thomas J. Wang and Nancy J. Brown

Circulation Research. 2018;122:1135-1150, originally published April 12, 2018
https://doi.org/10.1161/CIRCRESAHA.118.311912

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Liberation From the P Value’s Tyranny
Lem Moyé and Michelle Cohen

Circulation Research. 2018;122:1046-1048, originally published April 12, 2018
https://doi.org/10.1161/CIRCRESAHA.117.312227

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Critical Evaluation of Data Requires Rigorous but Broadly Based Statistical InferenceResponse by Lem Moyé and Michelle Cohen
Nancy J. Cox and Jennifer E. Below

Circulation Research. 2018;122:1049-1051, originally published April 12, 2018
https://doi.org/10.1161/CIRCRESAHA.118.312530

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It’s the Metabolism That Makes Macrophages Detectable in the Magnetic Resonance ScannerImmune Cell Detection by Hyperpolarized ¹³C Magnetic Resonance Imaging
Wolfgang R. Bauer, Constantin Lapa and Theresa Reiter

Circulation Research. 2018;122:1039-1040, originally published April 12, 2018
https://doi.org/10.1161/CIRCRESAHA.118.312901

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Reflection of Cardioprotection by Remote Ischemic Perconditioning in Attenuated ST-Segment Elevation During Ongoing Coronary Occlusion in PigsNovelty and SignificanceEvidence for Cardioprotection From Ischemic Injury
Petra Kleinbongard, Georgios Amanakis, Andreas Skyschally and Gerd Heusch

Circulation Research. 2018;122:1102-1108, originally published February 21, 2018
https://doi.org/10.1161/CIRCRESAHA.118.312784

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Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast ActivationNovelty and Significance
Ying-Chun Shih, Chao-Ling Chen, Yan Zhang, Rebecca L. Mellor, Evelyn M. Kanter, Yun Fang, Hua-Chi Wang, Chen-Ting Hung, Jing-Yi Nong, Hui-Ju Chen, Tzu-Han Lee, Yi-Shuan Tseng, Chiung-Nien Chen, Chau-Chung Wu, Shuei-Liong Lin, Kathryn A. Yamada, Jeanne M. Nerbonne and Kai-Chien Yang

Circulation Research. 2018;122:1052-1068, originally published March 13, 2018
https://doi.org/10.1161/CIRCRESAHA.117.312130

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Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic ResonanceNovelty and Significance
Andrew J.M. Lewis, Jack J. Miller, Angus Z. Lau, Mary K. Curtis, Oliver J. Rider, Robin P. Choudhury, Stefan Neubauer, Charles H. Cunningham, Carolyn A. Carr and Damian J. Tyler

Circulation Research. 2018;122:1084-1093, originally published February 12, 2018
https://doi.org/10.1161/CIRCRESAHA.117.312535

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S1P–S1PR2 Axis Mediates Homing of Muse Cells Into Damaged Heart for Long-Lasting Tissue Repair and Functional Recovery After Acute Myocardial InfarctionNovelty and Significance
Yoshihisa Yamada, Shohei Wakao, Yoshihiro Kushida, Shingo Minatoguchi, Atsushi Mikami, Kenshi Higashi, Shinya Baba, Taeko Shigemoto, Yasumasa Kuroda, Hiromitsu Kanamori, Mohamad Amin, Masanori Kawasaki, Kazuhiko Nishigaki, Masato Taoka, Toshiaki Isobe, Chisako Muramatsu, Mari Dezawa and Shinya Minatoguchi

Circulation Research. 2018;122:1069-1083, originally published February 23, 2018
https://doi.org/10.1161/CIRCRESAHA.117.311648

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