Genetics

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Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte ProliferationNovelty and Significance
Donghui Zhang, Yifei Li, Danielle Heims-Waldron, Vassilios Bezzerides, Silvia Guatimosim, Yuxuan Guo, Fei Gu, Pingzhu Zhou, Zhiqiang Lin, Qing Ma, Jianming Liu, Da-Zhi Wang and William T. Pu

Circulation Research. 2018;122:74-87, originally published October 11, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311349

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Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes PatientsNovelty and SignificanceRescue by α-Ketoglutarate and TET-TDG Functional Reactivation
Francesco Spallotta, Chiara Cencioni, Sandra Atlante, Davide Garella, Mattia Cocco, Mattia Mori, Raffaella Mastrocola, Carsten Kuenne, Stefan Guenther, Simona Nanni, Valerio Azzimato, Sven Zukunft, Angela Kornberger, Duran Sürün, Frank Schnütgen, Harald von Melchner, Antonella Di Stilo, Manuela Aragno, Maarten Braspenning, Wim van Criekinge, Miles J. De Blasio, Rebecca H. Ritchie, Germana Zaccagnini, Fabio Martelli, Antonella Farsetti, Ingrid Fleming, Thomas Braun, Andres Beiras-Fernandez, Bruno Botta, Massimo Collino, Massimo Bertinaria, Andreas M. Zeiher and Carlo Gaetano

Circulation Research. 2018;122:31-46, originally published November 20, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311300

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Lessening the Burden of Familial Hypercholesterolemia Using Health Information Technology
Maya S. Safarova and Iftikhar J. Kullo

Circulation Research. 2018;122:26-27, originally published January 4, 2018
https://doi.org/10.1161/CIRCRESAHA.117.312319

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Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic CellsNovelty and Significance
Ming-Tao Zhao, Ning-Yi Shao, Shijun Hu, Ning Ma, Rajini Srinivasan, Fereshteh Jahanbani, Jaecheol Lee, Sophia L. Zhang, Michael P. Snyder and Joseph C. Wu

Circulation Research. 2017;121:1237-1250, originally published October 13, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311367

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It Takes a Village to Train a Scientist
David Y. Barefield

Circulation Research. 2017;121:908-909, originally published September 28, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311485

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Gene Editing for the HeartCorrecting Dystrophin Mutations
Elizabeth M. McNally

Circulation Research. 2017;121:896-898, originally published September 28, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311865

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Pediatric Cardiomyopathies
Teresa M. Lee, Daphne T. Hsu, Paul Kantor, Jeffrey A. Towbin, Stephanie M. Ware, Steven D. Colan, Wendy K. Chung, John L. Jefferies, Joseph W. Rossano, Chesney D. Castleberry, Linda J. Addonizio, Ashwin K. Lal, Jacqueline M. Lamour, Erin M. Miller, Philip T. Thrush, Jason D. Czachor, Hiedy Razoky, Ashley Hill and Steven E. Lipshultz

Circulation Research. 2017;121:855-873, originally published September 14, 2017
https://doi.org/10.1161/CIRCRESAHA.116.309386

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Inflammatory Cardiomyopathic Syndromes
Barry H. Trachtenberg and Joshua M. Hare

Circulation Research. 2017;121:803-818, originally published September 14, 2017
https://doi.org/10.1161/CIRCRESAHA.117.310221

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Dilated CardiomyopathyGenetic Determinants and Mechanisms
Elizabeth M. McNally and Luisa Mestroni

Circulation Research. 2017;121:731-748, originally published September 14, 2017
https://doi.org/10.1161/CIRCRESAHA.116.309396

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Hypertrophic CardiomyopathyGenetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy
Ali J. Marian and Eugene Braunwald

Circulation Research. 2017;121:749-770, originally published September 14, 2017
https://doi.org/10.1161/CIRCRESAHA.117.311059

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